Diethylamine → Methyl 4-(4-hydroxybutyl)benzoate

HRID 2327031Notes

Reaction equation

HRID 2327031 reaction equation
[Br:20][c:21]1[cH:22][cH:23][c:24]([C:25](=[O:26])[O:27][CH3:28])[cH:29][cH:30]1.[CH2:31]([CH2:32][C:33]#[CH:34])[OH:35].[CH2:36]([NH:37][CH2:38][CH3:39])[CH3:40].[Cu:44][I:45].[Pd:41]([Cl:42])[Cl:43].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[c:21]1([CH2:34][CH2:33][CH2:32][CH2:31][OH:35])[cH:22][cH:23][c:24]([C:25](=[O:26])[O:27][CH3:28])[cH:29][cH:30]1

Participants

7

Reactant 6

HCID 8021DiethylamineHCID 11776TriphenylphosphineHCID 12081Methyl 4-bromobenzoateHCID 135663-Butyn-1-OLHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

Product 1

HCID 14603109Methyl 4-(4-hydroxybutyl)benzoate

Sources & evidence

ORD record
ord-79bd97a37b1843d39176559ecf598887
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…