Methanol → 8-Benzoyl-2-cyclohexyl-2,8-diazaspiro[4.5]decan-1-one
Reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[CH3:48][OH:49].[CH:10]1([N:16]2[C:17](=[O:26])[C:18]3([CH2:19][CH2:20]2)[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]1.[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[F:36][C:37]([F:38])([F:39])[C:40]([OH:41])=[O:42]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:23]1[CH2:22][CH2:21][C:18]2([C:17](=[O:26])[N:16]([CH:10]3[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]3)[CH2:20][CH2:19]2)[CH2:25][CH2:24]1Participants
7
Sources & evidence
- ORD record
- ord-05daa323d43e425db30f98632136888b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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