Water → 3-Amino-6-bromo-N-pyridin-3-ylpyrazine-2-carboxamide

HRID 2329296Notes

Reaction equation

[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[NH2:12][c:13]1[cH:14][n:15][cH:16][cH:17][cH:18]1.[NH2:1][c:2]1[c:3]([C:9](=[O:10])[OH:11])[n:4][c:5]([Br:8])[cH:6][n:7]1.[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH2:50].[P-:26]([F:27])([F:28])([F:29])([F:30])([F:31])[F:32].[n:33]1([O:34][C:35]([N:36]([CH3:37])[CH3:38])=[N+:39]([CH3:40])[CH3:41])[c:42]2[n:43][cH:44][cH:45][cH:46][c:47]2[n:48][n:49]1>>[NH2:1][c:2]1[c:3]([C:9](=[O:11])[NH:12][c:13]2[cH:14][n:15][cH:16][cH:17][cH:18]2)[n:4][c:5]([Br:8])[cH:6][n:7]1

Participants

Reactant 7

HCID 962Water

HCID 6228Dimethylformamide

HCID 8471Triethylamine

HCID 9886Hexafluorophosphate

HCID 100093-Aminopyridine

HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

HCID 185216003-Amino-6-bromopyrazine-2-carboxylic acid

Product 1

HCID 104021623-Amino-6-bromo-N-pyridin-3-ylpyrazine-2-carboxamide

Sources & evidence

ORD record: ord-45aa65fe9c2047b182f568d1045b99ad
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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