Water → 3-[[2,6-Dichloro-4-[4-[4-(trifluoromethyl)piperidine-1-carbonyl]phenyl]phenyl]methyl]-1-(4-hydroxypiperidin-1-yl)pyrrolidin-2-one
Reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:64][CH2:65][O:66][C:67](=[O:68])[CH3:69].[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][cH:35][c:36]([C:39](=[O:40])[N:41]3[CH2:42][CH2:43][CH:44]([C:47]([F:48])([F:49])[F:50])[CH2:45][CH2:46]3)[cH:37][cH:38]2)[cH:5][c:6]([Cl:32])[c:7]1[CH2:8][CH:9]1[C:10](=[O:31])[N:11]([N:14]2[CH2:15][CH2:16][CH:17]([O:20][Si:21]([CH:22]([CH3:23])[CH3:24])([CH:25]([CH3:26])[CH3:27])[CH:28]([CH3:29])[CH3:30])[CH2:18][CH2:19]2)[CH2:12][CH2:13]1.[F:57][C:58]([F:59])([F:60])[C:61]([OH:62])=[O:63].[OH2:56]>>[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][cH:35][c:36]([C:39](=[O:40])[N:41]3[CH2:42][CH2:43][CH:44]([C:47]([F:48])([F:49])[F:50])[CH2:45][CH2:46]3)[cH:37][cH:38]2)[cH:5][c:6]([Cl:32])[c:7]1[CH2:8][CH:9]1[C:10](=[O:31])[N:11]([N:14]2[CH2:15][CH2:16][CH:17]([OH:20])[CH2:18][CH2:19]2)[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e8c647891ac14936bbd27a8325ee6046
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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