Water → 3-(4-Bromo-1-naphthalenyl)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)isoxazole
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:12]([O-:13])=[N:14][OH:15])[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[Cl:16][N:17]1[C:18](=[O:19])[CH2:20][CH2:21][C:22]1=[O:23].[Cl:24][c:25]1[cH:26][c:27]([Cl:37])[cH:28][c:29]([C:31](=[CH2:32])[C:33]([F:34])([F:35])[F:36])[cH:30]1.[OH2:50]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:12]2=[N:14][O:15][C:31]([c:29]3[cH:28][c:27]([Cl:37])[cH:26][c:25]([Cl:24])[cH:30]3)([C:33]([F:34])([F:35])[F:36])[CH2:32]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c291aa79009c4971816677cddfd8eaf3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…