Tetrahydrofuran → Ethyl 2-(2,3-difluorobenzyl)-3-oxobutyrate
Reaction equation
[Br:1][CH2:2][c:3]1[c:4]([F:10])[c:5]([F:9])[cH:6][cH:7][cH:8]1.[C:12]([CH2:13][C:14](=[O:15])[CH3:16])(=[O:17])[O:18][CH2:19][CH3:20].[Na:11].[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1>>[CH2:2]([c:3]1[c:4]([F:10])[c:5]([F:9])[cH:6][cH:7][cH:8]1)[CH:13]([C:12](=[O:17])[O:18][CH2:19][CH3:20])[C:14](=[O:15])[CH3:16]Participants
5
Sources & evidence
- ORD record
- ord-838b54fc18d149b2a316b3f13f6796da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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