Hydrochloric Acid → 1-(trifluoromethyl)cyclohexanol

HRID 2335095Notes

Reaction equation

HRID 2335095 reaction equation
[CH3:1][Si:2]([CH3:3])([CH3:4])[F:5].[CH3:22][CH2:23][CH2:24][CH2:25][N+:26]([CH2:27][CH2:28][CH2:29][CH3:30])([CH2:31][CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH2:37][CH3:38].[ClH:39].[F-:21].[F:13][C:14]([F:15])([F:16])[Si:17]([CH3:18])([CH3:19])[CH3:20].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[O:6]=[C:7]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1.[SiH3:40][O:41][SiH3:42]>>[OH:6][C:7]1([C:14]([F:13])([F:15])[F:16])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 7967CyclohexanoneHCID 8028TetrahydrofuranHCID 9869FluorotrimethylsilaneHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 123318DisiloxaneHCID 552549(Trifluoromethyl)trimethylsilane

Product 1

HCID 112752281-(trifluoromethyl)cyclohexanol

Sources & evidence

ORD record
ord-442f397e46a240f6b2f1da37b9bc5d38
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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