Hydrogen Bromide → 4-Ethoxycinnamoylpiperazine

HRID 2335852Notes

Reaction equation

HRID 2335852 reaction equation
[BrH:45].[CH2:19]([O:20][c:21]1[cH:22][cH:23][c:24]([CH:25]=[CH:26][C:27]([Cl:28])=[O:29])[cH:30][cH:31]1)[CH3:32].[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][cH:6][c:7]([CH:8]=[CH:9][C:10](=[O:11])[OH:12])[cH:13][cH:14]1.[CH3:51][CH2:52][OH:53].[NH:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1.[OH2:33].[OH2:34].[OH2:35].[OH2:36].[OH2:37].[OH2:38].[S:15]([Cl:16])([Cl:17])=[O:18]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][cH:6][c:7]([CH:8]=[CH:9][C:10](=[O:12])[N:39]2[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]2)[cH:13][cH:14]1

Participants

9

Reactant 8

HCID 260Hydrogen BromideHCID 702EthanolHCID 962Water6×HCID 4837PiperazineHCID 8028TetrahydrofuranHCID 24386Thionyl ChlorideHCID 2955753-(4-Ethoxyphenyl)prop-2-enoic acidHCID 53411295HCID 53411295, compound

Product 1

HCID 544061044-Ethoxycinnamoylpiperazine

Sources & evidence

ORD record
ord-23e2a88da1ba41a3a11aa4b68faa1573
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…