Tetrahydrofuran → HCID 21070488, compound

HRID 2336425Notes

Reaction equation

HRID 2336425 reaction equation
[Br:35][CH2:36][CH2:37][OH:38].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][CH:24]([NH2:27])[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][CH:24]([NH:27][CH2:36][CH2:37][OH:38])[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 108982-BromoethanolHCID 21070474Trans-[4-Amino-2-(4-amino-cyclohexylamino)-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone

Product 1

HCID 21070488HCID 21070488, compound

Sources & evidence

ORD record
ord-b31c192f078c43e9bf914c9c3d9d8ec2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…