Ammonium → 4-(1-Methylpiperidin-4-yloxy)-3-trifluoromethylbenzonitrile
Reaction equation
[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:7][N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[Cl-:28].[F:15][c:16]1[c:17]([C:24]([F:25])([F:26])[F:27])[cH:18][c:19]([C:20]#[N:21])[cH:22][cH:23]1.[K+:6].[NH4+:29].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:35]>>[CH3:7][N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:16]2[c:17]([C:24]([F:25])([F:26])[F:27])[cH:18][c:19]([C:20]#[N:21])[cH:22][cH:23]2)[CH2:12][CH2:13]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-4a118ab158894e9786cf31853cd42f07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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