1-Bromo-3-chloropropane → 3-(3-Chloropropyl)-1-[2-fluoro-4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Reaction equation
[Br:18][CH2:19][CH2:20][CH2:21][Cl:22].[CH:28]([N:29]([CH:30]([CH3:31])[CH3:32])[CH2:33][CH3:34])([CH3:35])[CH3:36].[F:1][c:2]1[c:3]([C:12]23[CH2:13][NH:14][CH2:15][CH:16]2[CH2:17]3)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[F:1][c:2]1[c:3]([C:12]23[CH2:13][N:14]([CH2:19][CH2:20][CH2:21][Cl:22])[CH2:15][CH:16]2[CH2:17]3)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-b7f387a0d8d4459a950706dc5b896d02
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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