Tetrahydrofuran → 4-[6-(2,4,6-Trifluoro-benzoylamino)-pyridin-2-yloxy]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH2:21][CH2:22][CH:23]([O:26][c:27]2[n:28][c:29]([NH2:33])[cH:30][cH:31][cH:32]2)[CH2:24][CH2:25]1.[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([F:12])[cH:8][c:9]([F:11])[cH:10]1>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:33][c:29]2[n:28][c:27]([O:26][CH:23]3[CH2:22][CH2:21][N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:25][CH2:24]3)[cH:32][cH:31][cH:30]2)[c:7]([F:12])[cH:8][c:9]([F:11])[cH:10]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-285c3235d1ce48adbd3d65e3e50367f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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