Dimethylformamide → 6-Bromo-2,4-difluoro-3-methoxybenzaldehyde
Reaction equation
[Br:21][c:22]1[cH:23][c:24]([F:31])[c:25]([O:29][CH3:30])[c:26]([F:28])[cH:27]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:14][CH:15]([N-:16][CH:17]([CH3:18])[CH3:19])[CH3:20].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[Li+:13].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[Br:21][c:22]1[cH:23][c:24]([F:31])[c:25]([O:29][CH3:30])[c:26]([F:28])[c:27]1[CH:33]=[O:32]Participants
8
Sources & evidence
- ORD record
- ord-c85b450dc70243c399a062dbb3a33dfc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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