HRID2338124

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID312

Chloride

Cl-

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID31275

1,4-Dioxane

C4H8O2

HCID3614103

Ethyl 2-bromothiazole-5-carboxylate

C6H6BrNO2S

HCID178506176

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)c1cnc(N2CC3CC2CN3c2cccc(C(F)(F)F)c2)s1

HCID72560778

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c177728656284576af535e1d9fb14587
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (10/10)

反应 SMILES

[Br:1][c:2]1[s:3][c:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[cH:5][n:6]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl-:12].[F:13][C:14]([c:15]1[cH:16][c:17]([N:21]2[CH:22]3[CH2:23][NH2+:24][CH:25]([CH2:26]2)[CH2:27]3)[cH:18][cH:19][cH:20]1)([F:28])[F:29].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[c:2]1([N:24]2[CH2:23][CH:22]3[N:21]([c:17]4[cH:16][c:15]([C:14]([F:13])([F:28])[F:29])[cH:20][cH:19][cH:18]4)[CH2:26][CH:25]2[CH2:27]3)[s:3][c:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[cH:5][n:6]1