1,2-Dichloroethane → 6-Chloro-2-methyl-1h-indole

HRID 2338623Notes

Reaction equation

HRID 2338623 reaction equation
[CH2:20]([SiH:21]([CH2:22][CH3:23])[CH2:24][CH3:25])[CH3:26].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][c:7]([CH2:11][OH:12])[nH:8][c:9]2[cH:10]1.[Cl:27][CH2:28][CH2:29][Cl:30].[OH:13][C:14]([C:15]([F:16])([F:17])[F:18])=[O:19]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][c:7]([CH3:11])[nH:8][c:9]2[cH:10]1

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 16115151(6-Chloro-1H-indol-2-yl)methanol

Product 1

HCID 2715536-Chloro-2-methyl-1h-indole

Sources & evidence

ORD record
ord-dc9ca99fc60941fc9b17cf0c97f464e6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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