Tetrahydrofuran → 2-Hydroxy-3-bromo-5-(1,1-dimethylethyl)-benzonitrile
Reaction equation
[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[F:16][C:17]([F:18])([F:19])[C:20]([O:21][C:22](=[O:23])[C:24]([F:25])([F:26])[F:27])=[O:28].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH:1][c:2]1[c:3]([CH:4]=[N:5][OH:6])[cH:7][c:8]([C:12]([CH3:13])([CH3:14])[CH3:15])[cH:9][c:10]1[Br:11]>>[OH:1][c:2]1[c:3]([C:4]#[N:5])[cH:7][c:8]([C:12]([CH3:13])([CH3:14])[CH3:15])[cH:9][c:10]1[Br:11]Participants
5
Sources & evidence
- ORD record
- ord-4039ea419900454ba972d2cffcfb5ade
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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