Isopropanol → 2-chloro-N-methyl-5-nitropyrimidin-4-amine

HRID 2341085Notes

Reaction equation

HRID 2341085 reaction equation
[CH3:12][NH2:13].[CH3:19][CH:20]([OH:21])[CH3:22].[Cl:1][c:2]1[n:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([Cl:8])[n:7]1.[O:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([NH:13][CH3:12])[n:7]1

Participants

5

Reactant 4

HCID 3776IsopropanolHCID 6329MethylamineHCID 8028TetrahydrofuranHCID 5212662,4-Dichloro-5-nitropyrimidine

Product 1

HCID 71472322-chloro-N-methyl-5-nitropyrimidin-4-amine

Sources & evidence

ORD record
ord-ff3c2dfe4ae24c8d810dd142c259625f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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