Hydrochloric Acid → 3-(1-cyano-1-methylethyl)-N-{3-[(2-{[(4,4-difluoropiperidin-1-yl)acetyl]amino}[1,3]thiazolo[5,4-d]pyrimidin-5-yl)amino]-4-methylphenyl}benzamide
Reaction equation
[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([NH:15][c:16]3[cH:17][c:18]([NH:23][C:24]([c:25]4[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]4)=[O:36])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][c:13]2[n:14]1.[ClH:44].[F:45][C:46]1([F:52])[CH2:47][CH2:48][NH:49][CH2:50][CH2:51]1.[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[OH2:53]>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([NH:15][c:16]3[cH:17][c:18]([NH:23][C:24]([c:25]4[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]4)=[O:36])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][c:13]2[n:14]1)[N:49]1[CH2:48][CH2:47][C:46]([F:45])([F:52])[CH2:51][CH2:50]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-8f7823dd173847d899466bb0f06c0e48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…