Triethylamine → 2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine

HRID 2342701Notes

Reaction equation

HRID 2342701 reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:8])[n:5][cH:6][cH:7]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:9][Si:10]([CH3:11])([CH3:12])[C:13]#[CH:14].[Cu:22][I:23]>>[c:2]1([C:14]#[C:13][Si:10]([CH3:9])([CH3:11])[CH3:12])[cH:3][c:4]([Cl:8])[n:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 38477704-Bromo-2-chloropyridine

Product 1

HCID 219853912-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine

Sources & evidence

ORD record
ord-77549d00cde6409ba8f5e45729df27d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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