Dichloromethane → N-Trifluoroacetyl-8-bromo-7-isopropoxy-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Reaction equation
[CH2:25]1[CH2:26][CH2:27][C:28]2=[N:33][CH2:32][CH2:31][CH2:30][N:29]2[CH2:34][CH2:35]1.[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[CH:21]([CH3:22])([CH3:23])[Br:24].[Cl:36][CH2:37][Cl:38].[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:18])[c:15]([OH:17])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)([F:19])[F:20]>>[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:18])[c:15]([O:17][CH:21]([CH3:22])[CH3:23])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)([F:19])[F:20]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b1f1fcd323554710a6abee6e22a1ab87
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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