Dichloromethane → Benzyl 4-Hydroxy-1-piperidinecarboxylate

HRID 2343892Notes

Reaction equation

HRID 2343892 reaction equation
[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[O:15][C:16](=[O:17])[Cl:18].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:26][CH2:27][Cl:28].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:16]([O:15][CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[O:17])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 79341Piperidin-4-ol

Product 1

HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-8bd789ce5dd64b8ab06f9a3250220e64
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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