Ammonium → Methyl 5-(2,2,2-trifluoroethoxy)pyrazine-2-carboxylate

HRID 2344678Notes

Reaction equation

HRID 2344678 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl-:31].[Cs+:5].[Cs+:6].[F:7][C:8]([F:9])([F:10])[S:11]([O:12][CH2:13][C:14]([F:15])([F:16])[F:17])(=[O:18])=[O:19].[NH4+:32].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[OH:20][c:21]1[n:22][cH:23][c:24]([C:27](=[O:28])[O:29][CH3:30])[n:25][cH:26]1>>[O:12]([CH2:13][C:14]([F:15])([F:16])[F:17])[c:21]1[n:22][cH:23][c:24]([C:27](=[O:28])[O:29][CH3:30])[n:25][cH:26]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 803662,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 104967Cesium cation2×HCID 178498852HCID 178498852, compound

Product 1

HCID 57827340Methyl 5-(2,2,2-trifluoroethoxy)pyrazine-2-carboxylate

Sources & evidence

ORD record
ord-b3ec99ccaa784b84a5868c5ff82bef86
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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