Acetate → tert-butyl 6-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

HRID 2344929Notes

Reaction equation

HRID 2344929 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][cH:15][c:16]([Br:22])[cH:17][c:18]3[C:19](=[O:21])[CH2:20]2)[CH2:23][CH2:24]1.[C:44]([CH:45]=[CH2:46])(=[O:47])[O:48][CH3:49].[O-:56][C:57]([CH3:58])=[O:59].[O-:60][C:61]([CH3:62])=[O:63].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[Pd+2:55].[c:25]1([P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][cH:15][c:16]([CH:46]=[CH:45][C:44](=[O:47])[O:48][CH3:49])[cH:17][c:18]3[C:19](=[O:21])[CH2:20]2)[CH2:23][CH2:24]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6228DimethylformamideHCID 7294Methyl AcrylateHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2794759tert-Butyl 6-bromo-4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate

Product 1

HCID 66932397tert-butyl 6-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

Sources & evidence

ORD record
ord-12453da8c7184bdd84d3bc01b88a70b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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