Water → N-(2,3-dihydroxypropyl)-5-[3-methyl-5-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]phenyl]-1,3-thiazole-2-carboxamide
Reaction equation
[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:73][N:74]([CH3:75])[CH:76]=[O:77].[CH3:7][c:8]1[cH:9][c:10](-[c:25]2[cH:26][n:27][c:28]([C:30](=[O:31])[OH:32])[s:29]2)[cH:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[n:20]2)[cH:13]1.[F:40][P-:41]([F:42])([F:43])([F:44])([F:45])[F:46].[NH2:1][CH2:2][CH:3]([CH2:4][OH:5])[OH:6].[OH2:78].[n:47]1([O:48][P+:49]([N:50]2[CH2:51][CH2:52][CH2:53][CH2:54]2)([N:55]2[CH2:56][CH2:57][CH2:58][CH2:59]2)[N:60]2[CH2:61][CH2:62][CH2:63][CH2:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][c:70]2[n:71][n:72]1>>[NH:1]([CH2:2][CH:3]([CH2:4][OH:5])[OH:6])[C:30]([c:28]1[n:27][cH:26][c:25](-[c:10]2[cH:9][c:8]([CH3:7])[cH:13][c:12]([NH:14][c:15]3[n:16][cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[n:20]3)[cH:11]2)[s:29]1)=[O:31]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b615cd207180404b8491593fc08cf8f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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