Tetrahydrofuran → N-{5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-fluorophenyl}-2,2,2-trifluoroacetamide
Reaction equation
[C:9](#[CH:10])[c:11]1[cH:12][cH:13][c:14]([F:24])[c:15]([NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])[cH:16]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[Cu:30][I:31]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:10]#[C:9][c:11]2[cH:12][cH:13][c:14]([F:24])[c:15]([NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])[cH:16]2)[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-dc0bd1c10e094179a768847a87cac6bf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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