Dimethylformamide → 5-[3-butyl-6-(1-methyl-piperidin-4-yloxy)-pyridazin-4-yl]-2-cyclohexyloxy-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzamide
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][n:7][c:8]([O:27][CH:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:9][c:10]1-[c:11]1[cH:12][cH:13][c:14]([O:20][CH:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[c:15]([C:16](=[O:17])[OH:18])[cH:19]1.[CH:59]([N:60]([CH:61]([CH3:62])[CH3:63])[CH2:64][CH3:65])([CH3:66])[CH3:67].[NH2:68][C:69]([CH2:70][OH:71])([CH3:72])[CH3:73].[O:74]=[CH:75][N:76]([CH3:77])[CH3:78].[P-:35]([F:36])([F:37])([F:38])([F:39])([F:40])[F:41].[n:42]1([O:43][C:44]([N:45]([CH3:46])[CH3:47])=[N+:48]([CH3:49])[CH3:50])[c:51]2[cH:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][n:7][c:8]([O:27][CH:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:9][c:10]1-[c:11]1[cH:12][cH:13][c:14]([O:20][CH:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[c:15]([C:16](=[O:17])[NH:68][C:69]([CH2:70][OH:71])([CH3:72])[CH3:73])[cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9f894e8e1f3e44388393a7d1ce941670
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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