Ammonium → 5-[4-(4-Ethoxy-2,3-difluorophenoxymethyl)cyclohexyl]-2-trimethylsilanylethynyltetrahydropyran-2-ol
Reaction equation
[CH2:12]([CH3:13])[O:14][c:15]1[c:16]([F:37])[c:17]([F:36])[c:18]([O:19][CH2:20][CH:21]2[CH2:22][CH2:23][CH:24]([CH:27]3[CH2:28][CH2:29][C:30](=[O:33])[O:31][CH2:32]3)[CH2:25][CH2:26]2)[cH:34][cH:35]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[CH:6].[CH3:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50].[Cl-:38].[NH4+:39]>>[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][C:30]1([OH:33])[CH2:29][CH2:28][CH:27]([CH:24]2[CH2:23][CH2:22][CH:21]([CH2:20][O:19][c:18]3[c:17]([F:36])[c:16]([F:37])[c:15]([O:14][CH2:12][CH3:13])[cH:35][cH:34]3)[CH2:26][CH2:25]2)[CH2:32][O:31]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2209bc0c999049e98ca509d829a414a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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