Water → 5-[(Trimethylsilyl)ethynyl]thiophen-2-ylmethyl Tert-butyldiphenylsilyl Ether

HRID 2348841Notes

Reaction equation

HRID 2348841 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[O:18][CH2:19][c:20]1[s:21][c:22]([Br:25])[cH:23][cH:24]1.[CH3:26][Si:27]([CH3:28])([CH3:29])[C:30]#[CH:31].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cu:39][I:40].[OH2:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[O:18][CH2:19][c:20]1[s:21][c:22]([C:31]#[C:30][Si:27]([CH3:26])([CH3:28])[CH3:29])[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 962WaterHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 22393098(5-Bromothiophen-2-yl)methyl Tert-butyldiphenylsilyl Ether

Product 1

HCID 223930945-[(Trimethylsilyl)ethynyl]thiophen-2-ylmethyl Tert-butyldiphenylsilyl Ether

Sources & evidence

ORD record
ord-b8ad339680af4a3981f1cbc897122ed7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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