Cyanide → N-[6-chloro-2-(3-cyanopyrrolidin-1-yl)quinolin-5-yl]-2-cyclohexylacetamide
Reaction equation
[C-:32]#[N:33].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Cl:1][c:2]1[c:3]([NH:22][C:23]([CH2:24][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]2)=[O:31])[c:4]2[cH:5][cH:6][c:7]([N:12]3[CH2:13][CH:14]([O:17][S:18]([CH3:19])(=[O:20])=[O:21])[CH2:15][CH2:16]3)[n:8][c:9]2[cH:10][cH:11]1.[Li+:34]>>[Cl:1][c:2]1[c:3]([NH:22][C:23]([CH2:24][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]2)=[O:31])[c:4]2[cH:5][cH:6][c:7]([N:12]3[CH2:13][CH:14]([C:32]#[N:33])[CH2:15][CH2:16]3)[n:8][c:9]2[cH:10][cH:11]1Participants
5
Sources & evidence
- ORD record
- ord-28ed35b882594002bb84c67ed44b4be7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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