Chloride → N-(2-hydroxytetrahydro-2H-pyran-4-yl)-[2,1,3]-benzoxadiazole-5-carboxamide

HRID 2350728Notes

Reaction equation

HRID 2350728 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[C:59]([O:60][CH2:61][CH3:62])(=[O:63])[CH3:64].[CH2:54]([O:55][CH2:56][CH3:57])[CH3:58].[CH3:68][OH:69].[CH3:70][CH2:71][N:72]([CH2:73][CH3:74])[CH2:75][CH3:76].[CH:50]([Cl:51])([Cl:52])[Cl:53].[Cl-:9].[Cl:47][CH2:48][Cl:49].[Cl:65][CH2:66][Cl:67].[K+:26].[K+:27].[NH2:1][CH:2]([CH2:3][CH2:4][OH:5])[CH2:6][CH2:7][OH:8].[OH:28][CH2:29][CH2:30][CH:31]([CH2:32][CH2:33][OH:34])[NH:35][C:36](=[O:37])[c:38]1[cH:39][c:40]2[c:41]([n:42][o:43][n:44]2)[cH:45][cH:46]1.[n:10]1[o:11][n:12][c:13]2[cH:14][c:15]([C:16]([OH:17])=[O:18])[cH:19][cH:20][c:21]12>>[OH:28][CH:29]1[CH2:30][CH:31]([NH:35][C:36](=[O:37])[c:38]2[cH:39][c:40]3[c:41]([n:42][o:43][n:44]3)[cH:45][cH:46]2)[CH2:32][CH2:33][O:34]1

Participants

13

Reactant 12

HCID 312ChlorideHCID 813Potassium Cation2×HCID 887MethanolHCID 3283Diethyl EtherHCID 6212ChloroformHCID 6344Dichloromethane2×HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 27354542,1,3-Benzoxadiazole-5-carboxylic acidHCID 211178053-Aminopentane-1,5-diolHCID 66725669N-(1,5-dihydroxypentan-3-yl)-[2,1,3]-benzoxadiazole-5-carboxamide

Product 1

HCID 25104754N-(2-hydroxytetrahydro-2H-pyran-4-yl)-[2,1,3]-benzoxadiazole-5-carboxamide

Sources & evidence

ORD record
ord-71e37f9889474312bbc3e8edb2812f63
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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