反应详情

Prepared analogously to Example 2 from 9-chloro-11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and (+)-2-[2-[(diethylamino)methyl]-piperidin-1-yl]ethanamine in a yield of 50% of theory. Colourless crystals, m.p. 169°-170° C. (from acetonitrile, using activated charcoal); [α]D20 =+11.88° (dilute hydrochloric acid).