Ethanolamine → HCID 13773459, compound

HRID 2352528Notes

Reaction equation

HRID 2352528 reaction equation
[C:1]([OH:22])(=O)[CH2:2][CH2:3][CH2:4][C:5]#[C:6][CH2:7][C:8]#[C:9][CH2:10][C:11]#[C:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C(N1C=CN=C1)(N1C=CN=C1)=O.[CH2:35]([CH2:37][NH2:38])[OH:36]>CN(C=O)C>[OH:36][CH2:35][CH2:37][NH:38][C:1](=[O:22])[CH2:2][CH2:3][CH2:4][C:5]#[C:6][CH2:7][C:8]#[C:9][CH2:10][C:11]#[C:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

5

Reactant 3

HCID 700EthanolamineHCID 17815,8,11-Eicosatriynoic acidHCID 682631,1'-Carbonyldiimidazole

Product 1

HCID 13773459HCID 13773459, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 8 g of 5,8,11-eicosatriynoic acid and 5.62 g of carbonyldiimidazole in 40 cm3 of anhydrous DMF is brought to 80° C. for 3 hours under an inert atmosphere. 3.25 g of ethanolamine are then added at 0° C. After 2 hours, it is verified by thin layer chromatography that the starting acid is completely converted.

Sources & evidence

ORD record
ord-63f35b0570484120befabf2548027892
Source dataset
uspto-grants-1989_10
Patent number
US04877789

Reaction notes

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