Tert-Butylamine → HCID 3378586, compound

HRID 2354989Notes

Reaction equation

HRID 2354989 reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH:2]=[CH2:3].[C:8]([NH2:12])([CH3:11])([CH3:10])[CH3:9]>>[CH2:6]([O:5][C:1](=[O:4])[CH2:2][CH2:3][N:12]([C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:3][CH2:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[CH3:7]

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 8821Ethyl Acrylate

Product 1

HCID 3378586HCID 3378586, compoundYield 14.5%

Procedure

A mixture of ethyl acrylate (0.735 mol) and tert-butyl amine (0.210 mol) was refluxed for 6 days. The crude mixture was purified by fractionated distillation in vacuo (5 mbar). One fraction was collected (boiling point: 120° C. at 5 mbar), yielding to 8.3 g of the desired product as a light yellow oil. MS (m/e): 274.4 (MH+, 100%).

Workup

  1. temperaturewas refluxed for 6 days
  2. distillationThe crude mixture was purified by fractionated distillation in vacuo (5 mbar)
  3. customOne fraction was collected (boiling point: 120° C. at 5 mbar)

Sources & evidence

ORD record
ord-547c085183ba4e469712cdce398c17bf
Source dataset
uspto-grants-2010_07
Patent number
US07754736B2

Reaction notes

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