反应详情

To a solution of about 558 mg of 1-(4-tetradecylphenoxy)-3-(triphenylmethoxy)-2-propanol in about 5 ml of dry dimethylformamide was added a prewashed suspension of about 66 mg of sodium hydride in about 2 ml of dimethylformamide followed by about 157 mg of iodomethane. The mixture was stirred under argon for about 2 hours, quenched slowly with water and extracted twice with ether:hexane (about 1:1). The extracts were combined, dried, and the solvents evaporated, giving about 560 mg of the desired title compound.

1. customquenched slowly with water
2. extractionextracted twice with ether
3. customdried
4. customthe solvents evaporated