Oxalyl chloride → HCID 86615502, compound

HRID 2358765Notes

Reaction equation

HRID 2358765 reaction equation
[F:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=2)[C:10](O)=[O:11])=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1.C(Cl)(=O)C([Cl:24])=O>CN(C=O)C>[F:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=2)[C:10]([Cl:24])=[O:11])=[C:4]([N+:18]([O-:20])=[O:19])[CH:3]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 61395640HCID 61395640, compound

Product 1

HCID 86615502HCID 86615502, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product from Example 181b (1.6 g, 5.6 mmol) was treated with oxalyl chloride (0.86 g, 6.7 mmol) and catalytic DMF at room temperature for 6 h. The excess oxalyl chloride was removed under vacuum. The residue was chased with benzene to \give the title compound (1.66 g, 94%).

Workup

  1. customThe excess oxalyl chloride was removed under vacuum

Sources & evidence

ORD record
ord-89ce06f72a464cb8b92caf7ed5d57535
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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