反应详情

A stirred mixture of 3-benzyloxybenzoic acid (22.0 g; 0.096 mol) and dry dimethylformamide (2 drops) in dry dichloromethane (100 cm3) was treated with oxalyl chloride (19 g; 0.15 mol) which was added in 4 approximately equal portions over ˜30 minutes. The mixture was stirred at room temperature until evolution of hydrogen chloride had ceased (˜6 hrs). The resulting colourless solution was evaporated in vacuo at 40° to constant weight to give a very pale tan oil that solidified rapidly to give the title compound as off-white needles.

1. additionwas added in 4 approximately equal portions over ˜30 minutes
2. custom(˜6 hrs)
3. customThe resulting colourless solution was evaporated in vacuo at 40° to constant weight
4. customto give a very pale tan oil that