Diethyl Oxalate → HCID 21314613, compound

HRID 236957Notes

Reaction equation

HRID 236957 reaction equation
[C:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][CH2:11]2)=[C:6]([Br:14])[C:5]=1[OH:15])(=[O:3])[CH3:2].[Na].[C:17](OCC)(=O)[C:18]([O:20][CH2:21][CH3:22])=[O:19]>>[Br:14][C:6]1[C:5]2[O:15][C:17]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:2][C:1](=[O:3])[C:4]=2[CH:13]=[C:12]2[C:7]=1[CH2:8][CH2:9][CH2:10][CH2:11]2

Participants

4

Reactant 3

HCID 7268Diethyl OxalateHCID 5360545SodiumHCID 20304527HCID 20304527, compound

Product 1

HCID 21314613HCID 21314613, compoundYield 72.3%

Procedure

The product of step (a) (5.3 g) was treated with sodium (2.3 g) and diethyl oxalate (7.3 g) under the conditions of Example 1(d) to give the title ester (5.0 g; 72%), mp 130°-132°.

Sources & evidence

ORD record
ord-5a5a52306df64f45b3f468e9e863d39b
Source dataset
uspto-grants-1979_06
Patent number
US04159273

Reaction notes

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