Methanesulfonic Acid → HCID 72673270, compound

HRID 2370056Notes

Reaction equation

HRID 2370056 reaction equation
[CH:1](=[C:8]1[NH:13][C:12](=[O:14])[C:11](=[CH:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:23][C:24]3[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=3)=[CH:18][N:17]=2)[NH:10][C:9]1=[O:30])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:31][S:32]([OH:35])(=[O:34])=[O:33]>CN(C=O)C>[CH3:31][S:32]([OH:35])(=[O:34])=[O:33].[CH:1](=[C:8]1[NH:13][C:12](=[O:14])[C:11](=[CH:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:23][C:24]3[CH:29]=[CH:28][N:27]=[CH:26][CH:25]=3)=[CH:18][N:17]=2)[NH:10][C:9]1=[O:30])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 70662762HCID 70662762, compound

Product 1

HCID 72673270HCID 72673270, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Compound 1 was co-precipitated with equal mole of methane sulfonic acid in DMF to get yellow powder as salt product Compound 2. mp 278° C.; 1H-NMR (400 MHz, DMSO): δ 2.31 (s, 3H), 5.52 (s, 2H), 6.73 (s, 1H), 6.80 (s, 1H), 7.30-8.80 (m, 12H), 10.28 (s, 1H), 12.29 (s, 1H).

Sources & evidence

ORD record
ord-62170ecf684c4617be0d737d5dc67c51
Source dataset
uspto-grants-2014_04
Patent number
US08710062B2

Reaction notes

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