反应详情

(E)-3-[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]-N-methyl-2-propenohydroxamic acid (1.85 g) is added to a solution of 0.85 g of tromethamine in 150 ml of methanol. The resulting solution is treated with charcoal, filtered and evaporated to dryness. The residue is crystallized from ether to obtain (E)-3-[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]-N-methyl-2-propenohydroxamic acid tromethamine salt, m.p. 134°-136°.

1. filtrationfiltered
2. customevaporated to dryness
3. customThe residue is crystallized from ether