Dimethylamine → 4-iodo-N,N-dimethylbenzamide

HRID 2373460Notes

Reaction equation

HRID 2373460 reaction equation
[I:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH3:11][NH:12][CH3:13].C(N(CC)CC)C>C(Cl)Cl>[I:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:12]([CH3:13])[CH3:11])=[O:7])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 674DimethylamineHCID 8471TriethylamineHCID 743734-Iodobenzoyl chloride

Product 1

HCID 8799334-iodo-N,N-dimethylbenzamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound is prepared in analogy to example 16a from 4-iodobenzoyl chloride, N,N-dimethylamine and triethylamine in CH2Cl2 as a yellowish oil, MS (ESI) 276.0 (M+H)+.

Sources & evidence

ORD record
ord-0d0247903d2a4ab5b0fc147926d634e7
Source dataset
uspto-grants-2008_12
Patent number
US07459480B2

Reaction notes

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