反应详情

This compound is prepared by the procedure described in step A of preparation 1.7, from 1.55 g of magnesium in 25 ml of THF, a solution of 11 g of 3-bromotoluene in 15 ml of THF and a solution of 10 g of 1-benzyl-4-piperidone in 30 ml of THF. The product obtained is chromatographed on silica gel, eluting with a DCM/MeOH (97/3; v/v) mixture. This gives 14.5 g of the expected product.

1. customThis compound is prepared by the procedure
2. customThe product obtained
3. customis chromatographed on silica gel
4. washeluting with a DCM/MeOH (97/3; v/v) mixture