Dimethylformamide → HCID 11325467, compound

HRID 2377783Notes

Reaction equation

HRID 2377783 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[C:6]([NH2:11])[CH:5]=1)([O-:3])=[O:2].[N:12]1[CH:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22](SN=C=O)=[CH:21][CH:20]=2)=[CH:14][CH:13]=1.[CH3:29][N:30](C)C=O>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]2[N:10]=[C:29]([NH:30][C:22]3[CH:21]=[CH:20][C:19]([O:18][C:15]4[CH:14]=[CH:13][N:12]=[CH:17][CH:16]=4)=[CH:24][CH:23]=3)[NH:11][C:6]=2[CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 51117914-Nitro-1,2-phenylenediamineHCID 86611513HCID 86611513, compound

Product 1

HCID 11325467HCID 11325467, compound

Procedure

For further reaction, 1006 mg of 4-nitro-1,2-phenylenediamine and 150 mg of the thioisocyanate 3 prepared are dissolved in 5 ml of dimethylformamide and stirred overnight at room temperature. After removal of the solvent, the residue was purified by MPLC chromatography (Rp 18), giving 126 mg of benzimidazolamine 4.

Workup

  1. customprepared
  2. customAfter removal of the solvent
  3. customthe residue was purified by MPLC chromatography (Rp 18)

Sources & evidence

ORD record
ord-41a87740575442d88f823289f5b836c9
Source dataset
uspto-grants-2008_12
Patent number
US07470702B2

Reaction notes

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