反应详情

A cooled (0° C.) solution of 2-bromo-4-(isopropylthio)-1-methylbenzene (123 mg) in THF (10 ml) was treated with a solution of oxone (580 mg) in water (6 ml). The reaction mixture was stirred at RT for 16 hours. The reaction mixture was diluted with ethyl acetate and washed with water. The organic layer was dried over sodium sulfate and concentrated to give the title compound (120 mg, 92%).

1. washwashed with water
2. dry with materialThe organic layer was dried over sodium sulfate
3. concentrationconcentrated