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HRID2395789

反应详情

EQUATION

反应方程式

HRID 2395789 的结构方程式

REACTANTS

反应物

3
结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

结构：O=C(O)c1cc2cc(OCc3ccccc3)ccc2[nH]1
HCID81146

5-(Phenylmethoxy)-1H-indole-2-carboxylic acid

C16H13NO3

结构：CCNc1cccnc1N1CCNCC1
HCID10130476

N-Ethyl-2-(piperazin-1-yl)pyridin-3-amine

C11H18N4

PRODUCTS

生成物

1
结构：CCNc1cccnc1N1CCN(C(=O)c2cc3cc(OCc4ccccc4)ccc3[nH]2)CC1
HCID489428

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Following the general procedure of EXAMPLE 16 and making non-critical variations but starting with 5-benzyloxyindole-2-carboxylic acid (1.0 g), 1-(3-ethylamino-2-pyridinyl)piperazine (International Publication WO 87/01706, 0.81 g), 1,1'-carbonyldiimidazole (0.61 g) and THF (7 ml), the title compound is obtained, mp 192°-193°.