Hydrogen Bromide → HCID 86734797, compound

HRID 2399117Notes

Reaction equation

HRID 2399117 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:8][CH2:9][CH2:10][CH2:11]O.[BrH:13]>>[BrH:13].[BrH:13].[NH2:8][CH2:9][CH2:10][CH2:11][S:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 90863-Amino-1-propanolHCID 178418616HCID 178418616, compound

Product 1

HCID 86734797HCID 86734797, compound

Procedure

A solution of 2-mercaptopyridine (2.2 g.) and 3-aminopropanol (1.14 ml.) in hydrobromic acid (48%, 25 ml.) was heated under reflux for 25 hours. The reaction mixture was evaporated to dryness and the oily residual solid recrystallised twice from ethanol to give 2-(3-aminopropylmercapto)pyridine dihydrobromide (3.2 g.) m.p. 186°-188°.

Workup

  1. temperatureunder reflux for 25 hours
  2. customThe reaction mixture was evaporated to dryness
  3. customthe oily residual solid recrystallised twice from ethanol

Sources & evidence

ORD record
ord-2204f4dc12e14fd3bed8a3cd38fa7832
Source dataset
uspto-grants-1977_05
Patent number
US04027026

Reaction notes

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