Piperidine → HCID 12931834, compound

HRID 2403153Notes

Reaction equation

C(O[C:4]1(O[Si](C)(C)C)[CH2:6][CH2:5]1)C.[NH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.C[Si]([C:22]#[N:23])(C)C>>[N:12]1([C:4]2([C:22]#[N:23])[CH2:5][CH2:6]2)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

Reactant 3

HCID 8082Piperidine

HCID 82115Trimethylsilyl cyanide

HCID 2734686(1-Ethoxycyclopropoxy)trimethylsilane

Product 1

HCID 12931834HCID 12931834, compoundYield 52%

Procedure

The reaction of (1-ethoxycyclopropoxy)trimethylsilane 13 and piperidine 14A with trimethylsilylcyanide yielded 1-(piperidin-1-yl)cyclopropanecarbonitrile as a yellow liquid (52%). MS ISP (m/e): 151.1 (68) [(M+H)]+, 149.2 (100).

Sources & evidence

ORD record: ord-faee700d5ce04444921eb7a87e714ecb
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08802665B2

Reaction notes

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