Phenethylamine → HCID 53868659, compound

HRID 2407630Notes

Reaction equation

HRID 2407630 reaction equation
[C:1]1([CH2:7][CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CCN(CC)CC.[CH:17]1([S:23](Cl)(=[O:25])=[O:24])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>C(Cl)Cl>[CH2:8]([NH:9][S:23]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1)(=[O:25])=[O:24])[CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 1001PhenethylamineHCID 8471TriethylamineHCID 237554Cyclohexanesulfonyl chloride

Product 1

HCID 53868659HCID 53868659, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a stirred solution of 2-phenylethylamine (0.60 g, 4.97 mmol) in 45 ml CH2Cl2 at room temperature was added Et3N (0.83 ml, 5.97 mmol). The mixture was stirred for 5 min, and then cyclohexanesulfonyl chloride (1.0 g, 5.47 mmol) was added at this temperature.

Sources & evidence

ORD record
ord-383e9e9503ac43b2b597456d96a7b874
Source dataset
uspto-grants-2014_08
Patent number
US08809584B2

Reaction notes

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