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HRID2411293

反应详情

EQUATION

反应方程式

HRID 2411293 的结构方程式

REACTANTS

反应物

2
结构：[I-].[Na+]
HCID5238

Sodium Iodide

INa

结构：Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1
HCID58484856

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(N2CCN(C(=O)c3ccc(I)cc3S(C)(=O)=O)CC2)c(C)c1
HCID71252305

未命名化合物

收率 82%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Cu][I]
催化剂HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

PROCEDURE

实验过程

Using (4-bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (979 mg) described in Preparation Example 110, sodium iodide (650 mg) and copper(I) iodide (205 mg) and by the reaction and treatment in the same manner as in Preparation Example 154, the title compound (886 mg) was obtained.