反应详情

A stirred solution of 4-amino-3-methylbenzoic acid (30.2 g), in dry dimethylformamide (300 ml), containing tributylamine (55 ml) was treated with n-hexadecanoyl chloride (61.0 g) in a similar manner to that described in Example 1(i) to give 4-(n-hexadecanamido)-3-methylbenzoic acid (21 g), in the form of white needles, m.p. 194°-196° C.