Allylamine → HCID 13370641, compound

HRID 2412959Notes

Reaction equation

HRID 2412959 reaction equation
[O:1]1[CH2:28][CH:2]1[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([C:9](=[O:27])[C:10]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[C:11]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[O:12]2)=[CH:7][CH:6]=1.[CH2:29]([NH2:32])[CH:30]=[CH2:31]>CC(O)C>[CH2:29]([NH:32][CH2:28][CH:2]([OH:1])[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([C:9](=[O:27])[C:10]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[C:11]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[O:12]2)=[CH:7][CH:6]=1)[CH:30]=[CH2:31]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 13370622HCID 13370622, compound

Product 1

HCID 13370641HCID 13370641, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Using Method B, the reaction of 7-(2,3-epoxypropoxy)-2,3-diphenychromone and allylamine afforded the desired amine as white needles, m.p. 119°-120° (iPrOH); yield, 82%. Its hydrochloride salt had m.p. 140°-142° (iPrOH/phCH3); containing water).

Sources & evidence

ORD record
ord-c1763ca604c14d099a688bf8c0eb958e
Source dataset
uspto-grants-1985_01
Patent number
US04495198

Reaction notes

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